publicaciones seleccionadas artículo académico Vasodilator and hypotensive effects of pure compounds and hydroalcoholic extract of Xenophyllum poposum (Phil) V.A Funk (Compositae) on rats. Phytomedicine. 50:99-108. 2018 Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2). Biochemical and Biophysical Research Communications. 493:1311-1317. 2017 Hydroalcoholic extract and pure compounds from Senecio nutans Sch. Bip (Compositae) induce vasodilation in rat aorta through endothelium-dependent and independent mechanisms. Journal of Ethnopharmacology. 192:99-107. 2016 Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 Signaling Pathway. Diabetes. 63:75-88. 2014 Mitochondrial fission is required for cardiomyocyte hypertrophy via a Ca2+-calcineurin signalling pathway. Journal of Cell Science. 2014 Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics. American Journal of Physiology-Endocrinology and Metabolism. 306:E1033-E1045. 2014 Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes. Biochemical Pharmacology. 91:323-336. 2014 Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832:1334-1344. 2013 Cell Death and Survival Through the Endoplasmic Reticulum- Mitochondrial Axis. Current Molecular Medicine. 13:317-329. 2013 Impaired cardiac autophagy in patients developing postoperative atrial fibrillation. The Journal of Thoracic and Cardiovascular Surgery. 143:451-459.e1. 2012 Protein Carbonylation and Adipocyte Mitochondrial Function. Journal of Biological Chemistry. 287:32967-32980. 2012 Dinámica mitocondrial: un potencial nuevo blanco terapéutico para la insuficiencia cardiaca. Revista Española de Cardiología. 64:916-923. 2011 The complex interplay between mitochondrial dynamics and cardiac metabolism. Journal of Bioenergetics and Biomembranes. 43:47-51. 2011
investigador principal en Búsqueda y validación de nuevas biomoléculas con actividad antitumoral de origen patagónico y antártico. IVM02-23 2023 - 2024